New York entomologist Mel Coplin (Ben Stiller) is having a mid-life crisis. He knows he is adopted, and has been content to accept his adopted parents (Mary Tyler Moore and George Segal) as his own – until now.
He loves his wife, Nancy (Patricia Arquette) and their newborn baby son but feels his life is incomplete without knowing his biological parents.
He enlists the help of professional “finder” Tina Kalb (Rea Leoni), a psychologist from an agency where Mel was adopted. She volunteers to track down his birth parents, provided she can tag along to record the journey for her doctoral thesis.
And so they all set out on a cross-country trek that brings them more surprises than they bargained for.
The trip develops into an escalating series of disasters as it becomes clear that the adoption agency’s record-keeping leaves much to be desired.
During the trip, Mel and Nancy’s marriage is tested as Mel finds himself lusting after the gorgeous Tina.
Nancy feels erotic stirrings of her own when the trio meets up with an old high school friend of hers, Paul (Josh Brolin), who still carries a torch for her.
Along the way, the list of Mel’s prospective parents includes an unhappy San Diego housewife (Celia Weston) obsessed with her knick-knack collection, and a scruffy, demented truck driver (David Patrick Kelly) who is on the run from the law and teaches Mel how to drive an 18-wheeler just well enough to plow it into a US post office.
Mary Tyler Moore gives a raucous comedy performance as the clinging adoptive mother with tons of attitude and nerves of steel, and late in the film, two seemingly mismatched actors – Lily Tomlin and Alan Alda – become one of the funniest married couples you’ll ever see.
Mel Coplin
Ben Stiller
Nancy Coplin
Patricia Arquette
Tina Kalb
Téa Leoni
Pearl Coplin
Mary Tyler Moore
Ed Coplin
George Segal
Richard Schlichting
Alan Alda
Mary Schlichting
Lily Tomlin
Paul Harmon
Richard Jenkins
Agent Tony Kent
Josh Brolin
Valerie Swaney
Celia Weston
Lonnie Schlichting
Glenn Fitzgerald
Jane
Beth Ostrosky
Sandra
Cynthia LaMontagne
Fritz Boudreau
David Patrick Kelly
Mitch
John Ford Noonan
Jill
Nadia Dajani
Roger
Shawn Michael Howard
Director
David O. Russell